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Img 7289
Img 7289


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IMG 7289 CTP 102 is an ongoing multi national open label 24 week Phase 2 study of IMG 7289 taken once daily in MF patients resistant to all approved therapies Key objectives are safety and reduction a in spleen volume

Lysine specific demethylase 1 LSD1 is a histone demethylase critical for self renewal potential of malignant stem cells and progenitor maturation Bomedemstat is an oral LSD1 inhibitor clinically active in patients with MPNs IMG 7289 CTP 102 is a global open label Phase 2 study evaluating bomedemstat dosed in MF patients NCT03136185

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IMG 7289

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IMG 7289


IMG 7289 CTP 201 was a global open label Phase 2b study of bomedemstat IMG 7289 MK 3543 taken once daily for 24 weeks in patients with ET resistant to or intolerant of at least one standard treatment NCT04254978

Aims IMG 7289 CTP 102 is an ongoing global open label Phase 2 study evaluating bomedemstat dosed QD in MF patients NCT03136185 Key eligibility criteria include patients intolerant refractory resistant or inadequately controlled by approved therapy and platelet count 100 x 109 L Key objectives are safety and reduction of spleen

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IMG 7289 Ferreting Out The Fun

img-7289-ferreting-out-the-fun
IMG 7289 Ferreting Out The Fun


IMG 7289 CTP 201 is a global open label Phase 2b study of bomedemstat taken once daily for 24 weeks in patients with ET who are resistant to or intolerant of at least one SOC treatment NCT04254978

Bomedmestat also known as IMG 7289 or MRK3543 the bis tosylate salt of IMG 241 MRK3543 was invented by Hugh Young Rienhoff Jr Michael Clare Amy Tapper and John McCall in 2014 The original composition of matter patent application was filed in 2014

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IMG 7289 Ray Dehler Flickr


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IMG 7289 Ferreting Out The Fun

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IMG 7289 Tracey Howard Flickr


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IMG 7289 Nelson Chen Flickr


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IMG 7289 GiraGira


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IMG 7289 jpg Adrian Scottow Flickr


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 IMG 7289
A Phase 2 Study Of The LSD1 Inhibitor Bomedemstat IMG 7289

https://ashpublications.org/blood/article/140...
Lysine specific demethylase 1 LSD1 is a histone demethylase critical for self renewal potential of malignant stem cells and progenitor maturation Bomedemstat is an oral LSD1 inhibitor clinically active in patients with MPNs IMG 7289 CTP 102 is a global open label Phase 2 study evaluating bomedemstat dosed in MF patients NCT03136185

 IMG 7289
A Phase 2 Study Of The LSD1 Inhibitor Img 7289 bomedemstat

https://ashpublications.org/blood/article/138...
IMG 7289 CTP 102 is a global open label Phase 1 2 study evaluating bomedemstat dosed once daily in MF patients NCT03136185 Data from this ongoing study are presented

Lysine specific demethylase 1 LSD1 is a histone demethylase critical for self renewal potential of malignant stem cells and progenitor maturation Bomedemstat is an oral LSD1 inhibitor clinically active in patients with MPNs IMG 7289 CTP 102 is a global open label Phase 2 study evaluating bomedemstat dosed in MF patients NCT03136185

IMG 7289 CTP 102 is a global open label Phase 1 2 study evaluating bomedemstat dosed once daily in MF patients NCT03136185 Data from this ongoing study are presented

img-7289-nelson-chen-flickr

IMG 7289 Nelson Chen Flickr

img-7289-tracey-howard-flickr

IMG 7289 Tracey Howard Flickr

img-7289-giragira

IMG 7289 GiraGira

img-7289-jpg-adrian-scottow-flickr

IMG 7289 jpg Adrian Scottow Flickr

img-7289-2-7-22am-2011-jan-30th-vincent-van-den-storme-flickr

IMG 7289 2 7 22am 2011 Jan 30th Vincent Van Den Storme Flickr

img-7289-tracey-howard-flickr

IMG 7289 Don Wan Flickr

img-7289-don-wan-flickr

IMG 7289 Don Wan Flickr

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